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Ozone as an alternative for thermal sanitization in purified water systems like mother tanks, pipe lines and user points.

Home Ozone as an alternative for thermal sanitization in purified water systems like mother tanks, pipe lines and user points.
1. The Biofilm Challenge: Why Ozone Wins
  • Biofilm Resistance: Biofilms act as protective “fortresses” for Gram-negative bacteria such as Pseudomonas, shielding them from conventional disinfection methods.
  • The Hot Water Limitation: Hot Water Sanitization (HWS) typically operates at 80°C–85°C. While effective against planktonic bacteria, heat often fails to fully penetrate thick biofilm matrices. During cooling, the system remains vulnerable to rapid re-colonization.
  • The Ozone Solution: Ozone physically dissolves the Extracellular Polymeric Substances (EPS) that bind biofilms. Maintaining a residual of 0.05–0.2 ppm in the storage tank and distribution loop prevents biofilm formation entirely, creating a continuous “Sanitize-While-You-Work” environment.
2. Operational Efficiency: Eliminating Water & Energy Waste
  • Zero Water Wastage: HWS requires dumping water during heating and cooling transitions to manage temperature spikes. Ozone treatment occurs at ambient conditions, ensuring 100% of purified water remains in the loop for production.
  • Energy Decoupling: Eliminating steam heat exchangers and electric heaters for sanitization can reduce energy consumption by up to 70% for this utility.
  • No Re-occurrence: Continuous ozone residual removes the “window of vulnerability” that exists between thermal sanitization cycles.
3. Infrastructure Integrity and Safety
  • Reduced Thermal Stress: Repeated heating and cooling cycles (80°C to 20°C) accelerate mechanical stress, rouge formation in SS316L piping, and gasket degradation. Ozone operates at ambient temperature, significantly extending infrastructure lifespan.
  • Instant Neutralization: Residual ozone is easily removed using UV De-ozonation (254 nm) at return or point-of-use locations, ensuring water entering production is completely ozone-free and product-safe.
4. Comparison Matrix: 2026 Pharma Standards
Parameter Hot Water Sanitization (HWS) Residual Ozone System
Sanitization Frequency Batch-based (Weekly / Daily) Continuous (24/7)
Biofilm Control Surface-level kill; re-occurrence likely Deep matrix destruction; no re-occurrence
Energy Impact High (Steam or Heat Generation Required) Low (Standard Electrical Feed)